Lifestyle and the gut microbiota

• The gut microbiota is an adaptive entity that coevolves with the human host.

• Diet, environment and hygiene practices affect the microbiota.

• Westernization-diseases, such as obesity, are associated to lifestyle determinants.

Sources

Cooperative Orthogonal Macromolecular Assemblies with Broad Spectrum Antiviral Activity, High Selectivity, and Resistance Mitigation - Macromolecules (ACS Publications)

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Precision treatments based on new immunotherapy discovery.

The 'antigens' are the specific 'flags' that damaged Cells use to notify that something in wrong...

The 'immune system' can follow this advertisements using the 'T-Cells'. If those flags changes then is time to destroy the affected Cell..

“We had suspected that the diversity of mutations we see in tumour evolution would be reflected by the antigens present on the cancer cells – but until now we had no proof.”

Sources

New immunotherapy discovery could give treatments the precision they need - Cancer Research UK - Science blog

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade | Science